Table of Contents

Chapter 1 INTRODUCTION

STUDY GOALS AND OBJECTIVES

STUDY BACKGROUND

SCOPE OF THE REPORT

INTENDED AUDIENCE

SOURCE OF INFORMATION AND METHODOLOGY

ANALYST'S CREDENTIALS

RELATED BCC RESEARCH REPORTS

BCC RESEARCH WEBSITE

DISCLAIMER

Chapter 2 EXECUTIVE SUMMARY

Chapter 3 MARKET OVERVIEW

Chapter 4 PROTEIN-LABELING MARKET BY APPLICATION

Chapter 5 MARKET ANALYSIS BY PRODUCT

Chapter 6 PROTEIN LABELING MARKET ANALYSIS BY LABELING METHOD

Chapter 7 COMPETITIVE LANDSCAPE

Chapter 8 PROTEIN-LABELING MARKET ANALYSIS BY REGION

Chapter 9 PATENT ANALYSIS

Chapter 10 COMPANY PROFILES

MARKET DEFINITION

MARKET EVOLUTION AND INNOVATION

QUALITY ASSURANCE AND CONTROL

GOOD LABORATORY PRACTICES

ENZYME CONJUGATES

FLUORESCENT PROBES

QUALITY CONTROL

SPACE

STANDARD OPERATING PROTOCOL

GOOD LABORATORY PRACTICE ELEMENTS

ROLE OF GOOD LABORATORY PRACTICES IN IN VITRO STUDIES

TECHNOLOGY TRENDS

DEVELOPMENT OF LABELING TOOLS

MARKET DYNAMICS

SLENDR TECHNIQUE

NEW BIOTIN LABELS

ITRAQ

MUTANT B-LACTAMASE TAG TECHNOLOGY

DRIVERS

RESTRAINTS

OPPORTUNITIES

Quality Control Applications

Quality Control Logs

PERSONNEL SAFETY

Protocol

Reports

Archives

Key Good Laboratory Practice Points

Facilities and Equipment

Characterization

Test Item Control Before Formulation

Equipment Suitability and Calibration

Maintenance

Good Laboratory Practice Standards for Laboratory Equipment

Increasing Investment in Research and Development Endeavors

Increase in Genome Sequencing Demand

Increasing Healthcare Expenditure

Increase in Proteomics Research

Protein-Labeling Product Application

Lack of Skilled Professionals

Effective Protein-Labeling Technology Pricing

Technological Advances in Protein Labeling

Physical Separation

CELL-BASED ASSAYS

FLUORESCENCE MICROSCOPY

MASS SPECTROMETRY

IMMUNOLOGICAL TECHNIQUES

PROTEIN MICROARRAY

HISTORY OF CELL-BASED ASSAYS

CELL-BASED ASSAY APPLICATIONS

ADVANCES IN CELL-BASED ASSAYS

FLUORESCENCE MICROSCOPY HISTORY

FLUORESCENT MICROSCOPY TECHNIQUES

FLUORESCENCE MICROSCOPY PROCEDURE

RECENT ADVANCES IN FLUORESCENT MICROSCOPY

MASS SPECTROMETRY HISTORY

FUNCTIONS OF A MASS SPECTROMETER

MASS SPECTROMETRY APPLICATIONS

METHODS USED FOR MASS SPECTROMETRY

MASS SPECTROMETRY ADVANCES

CLINICAL IMMUNOLOGY APPLICATIONS

ADVANCES IN IMMUNOLOGICAL TECHNIQUES

PROTEIN MICROARRAY TYPES

PROTEIN ARRAY CLINICAL APPLICATIONS

ELISA

PROTEIN MICROARRAY ADVANTAGES

Fluorescent Microscope Functioning

Fluorescent Microscopy Applications

Mass Spectrometers

Matrix-Assisted Laser Desorption

Protocol for Data Acquisition Through Matrix-Assisted Laser Desorption Time of Flight

Immunoassay

Radioimmunoassay

Immunoprecipitation

Immunoelectrophoresis

Immunofluorescence

Immunohistochemistry

Immunocytochemistry

ELISA Types

Immunomonitoring

Immunomonitoring Application

Diabetes Mellitus

Infectious Diseases

KITS

REAGENTS

SERVICES

ENZYMES

HORSERADISH PEROXIDASE

ALKALINE PHOSPHATASE

MONOCLONAL ANTIBODIES

CHIMERIC MONOCLONAL ANTIBODIES

HUMAN MONOCLONAL ANTIBODIES

PROBES/TAGS

PROTEINS

BLOCKING BUFFERS

IODINATION REAGENTS

ELUTION BUFFERS

LABELING METHOD TYPES

IN VITRO LABELING

IN VIVO LABELING

BIOORTHOGONAL LABELING

Nanoparticle Labeling

Site-Specific Labeling

Dye-Based Labeling

Co-Translational Labeling

Enzymatic Labeling

Radioactive Labeling

Photoreactive Labeling

Nanoparticle Applications: A Biological Perspective

Nanoparticles Use in Protein Labeling

Luminescent Particles as Nanoparticles for Protein Labeling

Site-Specific Protein Labeling Using an Integration of Unnatural Amino Acids

Site-Specific Protein-Labeling Using Protein Targeting Sequences

Site-Specif Protein Labeling Using Peptide Targeting Sequences

Reactive Fluorescent Dyes

Amine-Reactive Dyes

Thiol-Reactive Dyes

Amine-Containing Dyes

Cadaverines

Carbonyl-Reactive Hydrazides

Avidin/Streptavidin-Biotin

Phalloidins

Formylglycine Generating Enzyme

Phosphopantetheinyl Transferase

Transglutaminase

Biotin Ligase

General Steps in Radioactive Labeling of Proteins

MERGERS AND ACQUISITIONS

PRODUCT LAUNCHES

PARTNERSHIPS AND COLLABORATIONS

OTHER STRATEGIES

NORTH AMERICA

EUROPE

ASIA-PACIFIC

REST OF THE WORLD

PATENT ANALYSIS BY MARKET PARTICIPANTS

PATENT ANALYSIS BY YEAR

ACTIVE MOTIF INC.

AGILENT TECHNOLOGIES INC.

BIO-RAD LABORATORIES

BIOTIUM INC.

CANDOR BIOSCIENCE GMBH

CAPRION BIOSCIENCES

F. HOFFMANN-LA ROCHE AG

GENERAL ELECTRIC COMPANY

INNOVA BIOSCIENCES LTD.

KANEKA CORP.

LI-COR BIOSCIENCES

LUMINEX CORP.

MERCK & COMPANY INC.

NANOTEMPER TECHNOLOGIES GMBH

NEW ENGLAND BIOLABS INC.

PERKINELMER INC.

PROMEGA COPRPORATION

SERACARE LIFE SCIENCES

TAKARA BIO USA INC.

THERMO FISHER SCIENTIFIC INC.

QIAGEN N.V.

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

PROTEIN-LABELING PRODUCT PORTFOLIO

Chapter 11 PATENTS BY REGION

List of Tables

Summary Table : GLOBAL PROTEIN-LABELING MARKET, BY REGION, THROUGH 2021

Table 1 : COMPARATIVE ANALYSIS OF U.S. FOOD AND DRUG ADMINISTRATION, ENVIRONMENTAL PROTECTION AGENCY AND ORGANIZATION FOR ECONOMIC COOPERATION AND DEVELOPMENT REGULATIONS BY PARAMETER

Table 2 : GLOBAL PROTEIN-LABELING MARKET, BY APPLICATION, THROUGH 2021

Table 3 : GLOBAL PROTEIN-LABELING MARKET FOR CELL-BASED ASSAYS, BY REGION, THROUGH 2021

Table 4 : GLOBAL PROTEIN-LABELING MARKET FOR FLUORESCENCE MICROSCOPY, BY REGION, THROUGH 2021

Table 5 : GLOBAL PROTEIN-LABELING MARKET FOR MASS SPECTROSCOPY, BY REGION, THROUGH 2021

Table 6 : GLOBAL PROTEIN-LABELING MARKET FOR IMMUNOLOGICAL TECHNIQUE APPLICATIONS, BY REGION, THROUGH 2021

Table 7 : GLOBAL PROTEIN-LABELING MARKET FOR PROTEIN MICROARRAYS, BY REGION, THROUGH 2021

Table 8 : GLOBAL PROTEIN-LABELING MARKET, BY PRODUCT, THROUGH 2021

Table 9 : GLOBAL PROTEIN-LABELING MARKET FOR KITS, BY REGION, THROUGH 2021

Table 10 : AMERSHAM CYDYE ANTIBODY LABELING KIT COMPONENTS

Table 11 : AMERSHAM CYDYE MONOCLONAL ANTIBODY LABELING KIT COMPONENTS

Table 12 : ZENON ANTIBODY LABELING KIT COMPONENTS

Table 13 : APEX ANTIBODY LABELING KIT COMPENENTS

Table 14 : MICROSCALE PROTEIN-LABELING KIT

Table 15 : SITECLICK ANTIBODY LABELING KIT

Table 16 : MOLECULAR PROBES' DSB-X BIOTIN PROTEIN-LABELING KIT

Table 17 : ROCHE BIOTIN PROTEIN-LABELING KIT

Table 18 : SNAP CELL STARTER KIT

Table 19 : CLIP CELL STARTER KIT

Table 20 : GLOBAL PROTEIN-LABELING MARKET FOR REAGENTS, BY TYPE, THROUGH 2021

Table 21 : GLOBAL PROTEIN-LABELING MARKET FOR REAGENTS, BY REGION, THROUGH 2021

Table 22 : GLOBAL PROTEIN-LABELING MARKET FOR ENZYMES, BY REGION, THROUGH 2021

Table 23 : THERMO FISHER SCIENTIFIC HORSERADISH PEROXIDASE

Table 24 : BIO-RAD HORSERADISH PEROXIDASE

Table 25 : THERMO FISHER SCIENTIFIC PIERCE ALKALINE PHOSPHATASE

Table 26 : NEW ENGLAND BIOLABS ALKALINE PHOSPHATES CALF INTESTINAL

Table 27 : GLOBAL PROTEIN-LABELING MARKET FOR MONOCLONAL ANTIBODIES, BY REGION, THROUGH 2021

Table 28 : CHIMERIC MONOCLONAL ANTIBODIES

Table 29 : HUMAN MONOCLONAL ANTIBODIES

Table 30 : GLOBAL PROTEIN-LABELING MARKET FOR PROBES/TAGS, BY REGION, THROUGH 2021

Table 31 : GLOBAL PROTEIN-LABELING MARKET FOR PROTEINS, BY REGION, THROUGH 2021

Table 32 : GLOBAL PROTEIN-LABELING MARKET FOR OTHER REAGENTS, BY REGION, THROUGH 2021

Table 33 : GLOBAL PROTEIN-LABELING MARKET FOR SERVICES, BY REGION, THROUGH 2021

Table 34 : GLOBAL PROTEIN-LABELING MARKET, BY LABELING METHOD, THROUGH 2021

Table 35 : GLOBAL PROTEIN-LABELING MARKET FOR IN VITRO LABELING METHODS, BY REGION, THROUGH 2021

Table 36 : GLOBAL PROTEIN-LABELING MARKET FOR IN VITRO LABELING METHODS BY TYPE, THROUGH 2021

Table 37 : GLOBAL PROTEIN-LABELING MARKET FOR NANOPARTICLE LABELING METHODS, BY REGION, THROUGH 2021

Table 38 : GLOBAL PROTEIN-LABELING MARKET FOR SITE-SPECIFIC LABELING, BY REGION, THROUGH 2021

Table 39 : SITE-SPECIFIC TAGS FOR PROTEIN-LABELING

Table 40 : GLOBAL PROTEIN-LABELING MARKET FOR DYE-BASED LABELING, BY REGION, THROUGH 2021

Table 41 : GLOBAL PROTEIN-LABELING MARKET FOR CO-TRANSLATIONAL LABELING, BY REGION, THROUGH 2021

Table 42 : GLOBAL PROTEIN-LABELING MARKET FOR ENZYMATIC LABELING METHOD, BY REGION, THROUGH 2021

Table 43 : GLOBAL PROTEIN-LABELING MARKET FOR IN VIVO LABELING, BY TYPE, THROUGH 2021

Table 44 : GLOBAL PROTEIN-LABELING MARKET FOR IN VIVO LABELING, BY REGION, THROUGH 2021

Table 45 : GLOBAL PROTEIN-LABELING MARKET FOR RADIOACTIVE LABELING METHOD, BY REGION, THROUGH 2021

Table 46 : RADIOACTIVE ELEMENTS

Table 47 : GLOBAL PROTEIN-LABELING MARKET FOR PHOTOREACTIVE LABELING METHOD, BY REGION, THROUGH 2021

Table 48 : GLOBAL PROTEIN-LABELING MARKET FOR BIORTHOGONAL LABELING METHOD, BY REGION, THROUGH 2021

Table 49 : KEY ACQUISTIONS, 2012-2016

Table 50 : KEY PRODUCT LAUNCHES, 2014-2016

Table 51 : KEY ANNOUNCED AGREEMENTS, 2014-2016

Table 52 : PARTNERSHIP AND COLLABORATION STRATEGIES, BY COMPANY, 2014-2016

Table 53 : NORTH AMERICAN PROTEIN-LABELING MARKET, BY PRODUCT TYPE, THROUGH 2021

Table 54 : EUROPEAN PROTEIN-LABELING MARKET, BY PRODUCT TYPE, THROUGH 2021

Table 55 : ASIA-PACIFIC PROTEIN-LABELING MARKET, BY PRODUCT TYPE, THROUGH 2021

Table 56 : REST OF THE WORLD PROTEIN-LABELING MARKET, BY PRODUCT TYPE, THROUGH 2021

Table 57 : ACTIVE MOTIF RECENT DEVELOPMENTS

Table 58 : AGILENT TECHNOLOGIES RECENT DEVELOPMENTS

Table 59 : AGILENT TECHNOLOGIES FINANCIALS, 2013-2015

Table 60 : BIO-RAD RECENT DEVELOPMENTS

Table 61 : BIO-RAD FINANCIALS 2013-2015

Table 62 : CANDOR RECENT DEVELOPMENTS

Table 63 : CAPRION RECENT DEVELOPMENTS

Table 64 : F. HOFFMANN-LA ROCHE AG RECENT DEVELOPMENTS

Table 65 : F. HOFFMANN-LA ROCHE AG FINANCIALS, 2013-2015

Table 66 : GENERAL ELECTRIC COMPANY RECENT DEVELOPMENTS

Table 67 : GENERAL ELECTRIC COMPANY FINANCIALS, 2013-2015

Table 68 : INNOVA BIOSCIENCES RECENT DEVELOPMENTS

Table 69 : KANEKA RECENT DEVELOPMENTS

Table 70 : KANEKA FINANCIALS, 2013-2015

Table 71 : LI-COR RECENT DEVELOPMENTS

Table 72 : LUMINEX, RECENT DEVELOPMENTS

Table 73 : LUMINEX FINANCIALS 2013-2015

Table 74 : MERCK RECENT DEVELOPMENTS

Table 75 : MERCK FINANCIALS, 2013-2015

Table 76 : NANOTEMPER RECENT DEVELOPMENTS

Table 77 : NEW ENGLAND BIOLABS INC. RECENT DEVELOPMENTS

Table 78 : PERKINELMER RECENT DEVELOPMENTS

Table 79 : PERKINELMER FINANCIALS, 2013-2015

Table 80 : PROMEGA RECENT DEVELOPMENTS

Table 81 : PROMEGA FINANCIALS, 2013-2015

Table 82 : SERACARE LIFE SCIENCES RECENT DEVELOPMENTS

Table 83 : TAKARA BIO RECENT DEVELOPMENTS

Table 84 : TAKARA BIO FINANCIALS, 2013-2015

Table 85 : THERMO FISHER RECENT DEVELOPMENTS

Table 86 : THERMO FISHER FINANCIALS, 2013-2015

Table 87 : QIAGEN RECENT DEVELOPMENTS

Table 88 : QIAGEN FINANCIALS, 2013-2015

Table 89 : NORTH AMERICAN PATENTS

Table 90 : EUROPEAN PATENTS

Table 91 : ASIA-PACIFIC REGION PATENTS

Table 92 : REST OF THE WORLD PATENTS

List of Figures

Summary Figure : GLOBAL PROTEIN-LABELING MARKET, BY REGION, 2015-2021

Figure 1 : KEY PROTEIN LABELS USED FOR PROTEIN LABELING

Figure 2 : COMPONENTS INVOLVED IN AN EFFECTIVE GOOD LABORATORY PRACTICE INVESTIGATION

Figure 3 : KEY GOOD LABORATORY PRACTICE ELEMENTS

Figure 4 : CELL-BASED ASSAY TYPES

Figure 5 : FLUORESCENCE MICROSCOPY PROTOCOL

Figure 6 : PROTEOMICS STUDY APPROACHES

Figure 7 : ELISA TYPES

Figure 8 : DIRECT ELISA PROTOCOL

Figure 9 : INDIRECT ELISA PROTOCOL

Figure 10 : COMPETITIVE ELISA PROTOCOL

Figure 11 : SANDWICH ELISA PROTOCOL

Figure 12 : METHODS FOR PROTEIN ARRAY DETECTION

Figure 13 : PROTEIN-LABELING PRODUCTS

Figure 14 : PROTEIN-LABELING METHODS

Figure 15 : KEY NANOPARTICLE FORMS USED IN BIOCONJUGATION

Figure 16 : REACTIVE FLUORESCENT AGENTS

Figure 17 : ENZYMES USED FOR PROTEIN LABELING

Figure 18 : STEPS INVOLVED IN VIVO PROTEIN-LABELING

Figure 19 : RADIOACTIVE LABELING OF PROTEINS

Figure 20 : GENERAL PROTOCOL FOR PHOTOLABELING OF PROTEINS

Figure 21 : KEY COMPETITIVE STRATEGIES, 2014-2016

Figure 22 : MERGER AND ACQUISTION STRATEGIES BY COMPANY, 2014-2016

Figure 23 : PRODUCT LAUNCH STRATEGIES, BY COMPANY, 2014-2016

Figure 24 : PARTNERSHIP AND COLLABORATION STRATEGIES, BY COMPANY, 2014-2016

Figure 25 : PARTNERSHIP AND COLLABORATION STRATEGIES, BY COMPANY, 2014-2016

Figure 26 : GLOBAL MARKET FOR PROTEIN-LABELING, BY REGION, 2015

Figure 27 : PATENTS GRANTED FOR PROTEIN-LABELING RESEARCH, BY REGION, 2015

Figure 28 : TOP 2,500 COMPANIES RESEARCH AND DEVELOPMENT INVESTMENT, BY REGION, 2014

Figure 29 : TOP 2,500 EUROPEAN COMPANIES RESEARCH AND DEVELOPMENT INVESTMENT, BY COUNTRY, 2014

Figure 30 : PATENTS REGISTERED AND APPROVED IN NORTH AMERICA, EUROPE, ASIA-PACIFIC AND THE REST OF THE WORLD, 2013-2016

Figure 31 : PATENT ANALYSIS, BY MARKET APPLICANT, 2013-2016

Figure 32 : PATENT ANALYSIS, BY YEAR, 2013-2016