Global Microbiome Sequencing Services Market – Industry Trends and Forecast to 2031

Global Microbiome Sequencing Services Market, By Technology (Sequencing By Synthesis (SBS), Sequencing By Ligation (SBL), Pyrosequencing, Sanger Sequencing, and Other Technologies), Laboratory Type (Dry Labs and Wet Labs), Research Type (Outsourced Research and Internal Research), Application (Shotgun Sequencing, Targeted Gene Sequencing, RNA Sequencing, Whole Genome Sequencing, and Other Applications), End User (Research and Academic Institutes, Pharmaceutical and Biotechnology Companies, and Others) – Industry Trends and Forecast to 2031.

Microbiome Sequencing Services Market Analysis and Size

The microbiome sequencing services market sees continuous advancement by integrating high-throughput technologies, AI-driven analytics, and multi-omics approaches. This evolution enables deeper insights into microbial communities, facilitating personalized medicine, agricultural enhancements, and environmental monitoring. Enhanced accuracy, efficiency, and scalability characterize the modern landscape, driving innovation and expanding applications across various sectors.           

For instance, according to the National Human Genome Research Institute of the United States National Institute of Health, as biomedical research projects and large-scale collaborations expand, genomic data generation is surging, reaching approximately 2 to 40 billion gigabytes annually as of April 2022.                     

Data Bridge Market Research analyses that the global microbiome sequencing services market size was valued at USD 1.65 billion in 2023, is projected to reach USD 6.68 billion by 2031, with a CAGR of 19.05% during the forecast period 2024 to 2031. This indicates that the market value. In addition to the insights on market scenarios such as market value, growth rate, segmentation, geographical coverage, and major players, the market reports curated by the Data Bridge Market Research also include depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.

Report Scope and Market Segmentation

Market Definition

Microbiome sequencing services analyze the genetic material of microorganisms in a specific environment, such as the human gut or soil. These services employ advanced techniques to identify and characterize microbial communities, offering insights into their diversity, composition, and functional potential. Such analysis is crucial for understanding microbial ecology and its implications for health, agriculture, and the environment.

Microbiome Sequencing Services Market Dynamics

Drivers

• Advancements in Next-Generation Sequencing (NGS) Technologies

Continuous advancements in next-generation sequencing (NGS) technologies have significantly enhanced sequencing speed, accuracy, and cost-effectiveness. This progress is a key driver propelling the growth of microbiome sequencing services. Faster, more precise, and affordable sequencing capabilities facilitate broader adoption of microbiome analysis across various industries and research domains, fueling market expansion.

For instance, a study in the April 2022 Journal of Clinical Investigation highlights how Next-generation sequencing (NGS) technology enhances comprehension of the human microbiome by identifying and characterizing unculturable microbes and predicting their functions. These innovations are anticipated to drive growth in microbiome sequencing services.

• Technological Integration and Automation

The integration of sequencing platforms with automated sample preparation and data analysis workflows enhances efficiency and reduces turnaround times. This technological advancement accelerates market growth by meeting the increasing demand for microbiome sequencing services while improving accessibility and affordability, thereby driving adoption across various research and application domains.

Opportunities

• Emerging Applications in Agriculture and Environmental Sciences

Microbiome sequencing in agriculture enhances crop yield, soil health, and environmental sustainability, driving demand for sequencing services. Farmers can optimize crop management practices, mitigate soil degradation, and develop eco-friendly solutions by analyzing microbial communities. This growing application presents significant growth opportunities for microbiome sequencing service providers in the agricultural and environmental sectors.

• Expansion of Biotechnology and Pharmaceutical Industries

Biotechnology and pharmaceutical sectors are integrating microbiome analysis into drug research and development, spurring demand for sequencing services. Microbiome insights are crucial for understanding drug efficacy, safety, and personalized treatments. This trend drives significant growth in microbiome sequencing services, catering to industry needs for comprehensive microbial data in therapeutic development pipelines. 

For instance, in March 2022, Microbiotica secured USD 67 million to advance its microbiome-based immuno-oncology research, earmarked for Phase 1b trials slated to commence later in the year. This substantial funding underscores the growing interest and investment in microbiome-related therapies for oncological applications.

Restraints/Challenges

• Ethical and Privacy Concerns

Microbiome sequencing raises ethical concerns due to collecting personal biological data, necessitating stringent adherence to privacy regulations and consent protocols. Ensuring data security is challenging, especially in large-scale research or clinical trials, highlighting the need for robust ethical frameworks to safeguard sensitive information responsibly. 

• High Cost of Microbiome Sequencing Services

Microbiome sequencing services can be prohibitively expensive due to the need for advanced technology and expertise. This cost presents accessibility barriers for smaller research entities or organizations with limited budgets, impeding their ability to utilize this technology for microbiome analysis and research purposes, potentially limiting the scope and depth of their scientific investigations in this field. 

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Recent Development

• In November 2023, QIAGEN NV launched Microbiome WGS (whole-genome sequencing) SeqSets, a streamlined Sample to Insight workflow enhancing efficiency and reproducibility in microbiome research, catering to researchers' needs for comprehensive solutions
• In June 2023, Zymo Research launched full-length 16S sequencing service, offering high-quality, full-length 16S rRNA gene sequencing, meeting researchers' demands for precise microbiome analysis tools
• In July 2020, Microba & Synlab collaborated to launch Microbiome Test in Europe and Latin America, evaluating gut bacterial species and their metabolic potential against healthy benchmarks, expanding access to whole-genome metagenomic sequencing and bioinformatics
• In March 2022, OraSure Technologies, under its Diversigen arm, introduced a service for gut microbiota sample metatranscriptomic sequencing and analysis, advancing capabilities in understanding microbiome dynamics for research and clinical applications

Microbiome Sequencing Services Market Scope

The market is segmented on the basis of technology, laboratory type, research type, application, and end-user. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Technology

• Sequencing By Synthesis (SBS)
• Sequencing By Ligation (SBL)
• Pyrosequencing
• Sanger Sequencing
• Other Technologies

 Laboratory Type

• Dry labs
• Wet Labs

 Research Type

• Outsourced Research
• Internal Research

 Application

• Shotgun Sequencing
• Targeted Gene Sequencing
• RNA Sequencing
• Whole Genome Sequencing
• Other Applications

 End User

• Research and Academic Institutes
• Pharmaceutical and Biotechnology Companies
• Others

Microbiome Sequencing Services Market Regional Analysis/Insights

The market is analysed and market size insights and trends are provided by country, technology, laboratory type, research type, application, and end-user as referenced above.

The countries covered in the market report are U.S., Canada, Mexico, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific, Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa, Brazil, Argentina, and Rest of South America.

North America is expected to dominate the market due to favorable reimbursement policies by governmental bodies in the region. This encourages adoption and facilitates accessibility, driving growth and innovation within the microbiome sequencing industry.

Asia-Pacific is expected to witness significant growth in the market, attributed to the burgeoning healthcare infrastructure development in the region. This trend underscores the region's increasing focus on advanced healthcare solutions, fostering market expansion during the forecast period.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.   

Healthcare Infrastructure growth Installed base and New Technology Penetration

The market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipment, installed base of different kind of products for market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the market. The data is available for historic period 2016-2021.

Competitive Landscape and Microbiome Sequencing Services Market Share Analysis

The market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to market.

Some of the major players operating in the market are:

• Baseclear B.V. (Netherlands)
• Zymo Research Corporation. (U.S.)
• Second Genome (U.S.)
• MR DNA (Molecular Research LP) (U.S.)
• Microbiome Therapeutics Innovation Group (U.S.)
• Microbiome Insights (Canada)
• Locus Biosciences, Inc. (U.S.)
• Mérieux NutriSciences Corporation (France)
• Clinical-Microbiomics A/S (Denmark)
• OpenBiome (U.S.)
• Shanghai Ruiyi Biotechnology Co., Ltd. (China)
• Rancho Bio Sciences (U.S.)
• Resphera Biosciences, LLC (U.S.)
• Diversigen (U.S.)
• Molzym GmbH & Co. KG (Germany)
• BioSpherex LLC (U.S.)
• TGen (U.S.)