Epigenetics Market Size and Forecasts (2021 - 2031), Global and Regional Share, Trends, and Growth Opportunity Analysis

Coverage: Epigenetics Market covers analysis By Product (Reagents, Kits, Enzymes, Instruments & Consumables, and Bioinformatics Tools), Technology (Histone Modification, DNA Methylation, and Others), Application (Oncology, Cardiovascular Diseases, and Others), and End Users (Academic & Research Institutes, Biotechnology & Pharmaceutical Companies, and Contract Research Organization), and Geography (North America, Europe, Asia Pacific, and South and Central America)

Publication Month : Apr 2024

  • Report Code : TIPHE100000971
  • Category : Healthcare IT
  • Status : Upcoming
  • No. of Pages : 160
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The epigenetics market is expected to grow from US$ 1509.99 million in 2022 to US$ 3092.48 million by 2028; it is expected to grow at a CAGR of 14.91% from 2022 to 2028.

A single or multiple changes in phenotype without changing the genotype which affects the cells. The changes occurred due to epigenetics are regular and natural and can also be influenced by several factors such as age, environment, lifestyle, and conditions of diseases. The modifications caused due to epigenetics can be noticeable commonly in the same way cells critically differentiate to end up as skin cells, liver cells, and brain cells. The epigenetic changes can also be resulted into diseases like cancer.

The epigenetics market is segmented on the basis of product, technology, application, end user, and geography. By geography, the market is broadly segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South & Central America. The report offers insights and in-depth analysis of the market, emphasizing parameters such as market trends, technological advancements, and market dynamics, along with the analysis of the competitive landscape of the leading market players.

Strategic Insights

Lucrative Regions for Epigenetics Market

Lucrative Regions for Epigenetics MarketMarket Insights

Declining Prices of Sequencing Drives Epigenetics Market Growth

The declining costs associated with sequencing strategies and methods influence the scale and scope of genomic research projects. The costs of DNA sequencing performed at the sequencing centers, which is funded by the Institutes, have been tracked by the National Human Genome Research Institute (NHGRI) for many years. This information has served as a key standard for establishing the DNA sequencing capacity and considering improvements in DNA sequencing technologies of the NHGRI Genome Sequencing Program (GSP).

In recent years, next-generation sequencing prices have declined substantially. The cost of first whole human genome sequencing was over US$3.7 billion in 2000, and the sequencing took 13 years for the completion. The sequencing costs reduced to US$1,000 in recent years, and the process requires less number of days. In 2000, cost for sequencing was US$ 3.7 billion, which dropped down to US$ 10 million in 2006 and declined to US$ 5,000 in 2012. Major market players such as Illumina and Roche have introduced breakthrough technologies that have enabled in the cost and time reduction in the sequencing.

Advances in the field of genomics and developments in different methods and strategies for sequencing drop the cost of sequencing, that upsurge the growth of the market.

Increasing Prevalence of Cancer Bolsters Epigenetic Market Growth

Study of epigenetic alterations in cancer, such as aberrant methylation and altered transcription factor binding, provides insights into tumorigenic pathways, which are located above the genetic code. The microarray and next-generation sequencing (NGS) technologies help detect altered methylation patterns and other epigenetic changes in cancer. Illumina works with cancer epigenetics experts to ensure its array and NGS solutions meet the rapidly growing needs of the field.

Cancer cases have been increasing tremendously in recent years, and the trend is anticipated to remain same in the coming years. Lifestyle changes have resulted in exposure to oncogenic factors. The American Cancer Society estimated 1,658,370 cancer cases to be detected in the US in 2015. Cancer can be cured if diagnosed and treated at an initial stage. Cancer sequencing using next-generation sequencing NGS methods provides more information. Additionally, epigenetics aids in cancer research, diagnostics, and treatment.

Thus, the increase in the number of cancer cases is expected to propel the epigenetics market growth in the coming years.

Product Insights

Based on product, the global epigenetics market is segmented into kits, reagents, enzymes, instruments & consumables, and bioinformatics tools. In 2017, the kits segment accounted for the highest market share, and it is expected to register a CAGR of 14.3% during the forecast period. Several kits are available in the market for gene expression analysis, MicroRNA analysis, SNP genotyping analysis, and other procedures. The easy-to-use kits are developed for the epigenetic processes to study DNA methylation and histone modifications (deacetylation and acetylation). Mostly, reagents are included in the kit, and each kit contains a detailed procedure that provides sensitive results rapidly. The epigenetic kits allow researchers to perform experiments and analyze epigenetic modifications efficiently and reliably by using antibodies directed against epitope tags or RNA-binding proteins. In epigenetics, highly efficient and fast processing kits are developed to perform the experiments. So, novel toolkits are developed by various companies. For instance, Merck KGaA offered several toolkits, including chromatin immunoprecipitation (ChIP) Kits, bisulfite DNA modification kits, RNA immunoprecipitation (RIP) Kits, for histone modification, DNA methylation, and RNA regulation. The quality control kits are efficient and fast for the preparation of the epigenetic procedures, which drives the growth of the epigenetics market in the kits segment. 

End User Insights

Based on end user, the global epigenetics market is segmented into academic & research institutes, biotechnology & pharmaceutical companies, and contract research organization. The market is dominated by the pharmaceutical & biotechnology companies segment. The market in the same segment is expected to grow significantly from 2022 to 2028. The growth of the biotechnological products market and various related markets has resulted into massive market consolidations between biotechnology and pharmaceutical companies for enhanced and better treatment options. The growing investments made by companies fueled the market growth in the pharmaceutical & biotechnology companies segment. In March 2017, Thermo Fisher Scientific acquired Core Informatics, a provider of leading cloud-based scientific data platforms. In January 2018, Abcam acquired AxioMx, Inc. to increase the supply of high-quality products generated from innovation. The technological development in molecular biology increased the sequencing procedures. Among the market leaders, the companies have manufactured and designed technologically-advanced epigenetics technology in the last few years. Advanced systems that dominate the market comprise Roche GS FLX (454) and Illumina HiSeq 2000 (Solexa). Various collaborations, investments made by the companies, and technological advancements bolstered the epigenetics market growth in the pharmaceutical & biotechnology companies segment.

Epigenetics Market, by Product – 2022 and 2028

Epigenetics Market, by Product – 2022 and 2028Product launches and mergers and acquisitions are among the highly-adopted strategies by the players operating in the global epigenetics market. A few of the recent key product developments are listed below:

  • In February 2016, Bio-Rad Laboratories Inc received CE IVD marking for its QX200 Droplet Digital PCR (ddPCR) System, the first digital PCR system with the CE IVD mark to use as an in-vitro diagnostic (IVD) in the European Union.
  • In January 2018, Abcam Plc entered an agreement with Roche to obtain exclusive rights to the product portfolio of Spring Bioscience Corporation in the research use only (RUO) field of use, comprising ~760 unique products. 

Epigenetics – Market Segmentation

Based on product, the epigenetics market is segmented into reagents, kits, enzymes, instruments & consumables, and bioinformatics tools. Based on technology, the market is segmented into histone modification, DNA methylation, and others. Based on application, the epigenetics market is segmented into oncology, cardiovascular diseases, and others. Based on end users, the market is segmented into academic & research institutes, biotechnology & pharmaceutical companies, and contract research organization. By geography, the epigenetics market is segmented into North America (the US, Canada, and Mexico), Europe (the UK, Germany, France, Italy, Spain, and the Rest of Europe), Asia Pacific (China, Japan, India, Australia, South Korea, and the Rest of Asia Pacific), the Middle East & Africa (the UAE, Saudi Arabia, South Africa, and the Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and the Rest of South & Central America)

Company Profiles

  • Merck KgaA
  • Thermo Fisher Scientific Inc
  • Abcam Plc
  • Agilent Technologies Inc
  • Qiagen
  • Bio-Rad Laboratories Inc
  • Active Motif
  • Perkin Elmer Inc
  • New England Biolabs
  • Illumina Inc

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REGIONAL FRAMEWORK
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Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Product, Technology, Application, and End Users

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

The List of Companies

1. Merck KGaA
2. Thermo Fisher Scientific, Inc.
3. Abcam plc
4. Agilent Technologies
5. Active Motif
6. QIAGEN
7. Bio-Rad Laboratories, Inc.
8. PerkinElmer Inc.
9. New England Biolabs (NEB)
10. Illumina, Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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